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The green channel of RGB images from picrosirius-red-stained lung sections was binarized with MATLAB software as previously reported 50 to quantify the infiltrates

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The Haller index, or the ratio of the transverse diameter of the chest to the anteroposterior diameter (the shortest distance between the anterior vertebral body and the sternum) is used for surgical decision making in pectus excavatum ( Figure 1, blue )

The compound suppresses fibrinogen expression (linked to cardiovascular risk) and reduces TGF-beta-driven fibrosis signaling

Still, we did not assay associated biomarkers to conclusively interrogate this possibility

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